Florid cystic endosalpingiosis of the uterus

A 73 year old woman presented with a right sided adnexal cystic mass. At la parotomy, this proved to be a benign serous ovarian cyst and an aggregation of thin walled sub-serosal and soft tissue cysts and spongy nodules up to 16 mm in diameter involving the side wall of the uterus and adjacent parame trium. These were removed by total abdominal hysterectomy and bilateral sal pingo-oophorectomy. Histologically, the cystic spaces and smaller acini wer e lined by benign tubo-endometrioid epithelium, with smaller areas typical of serious differentiation and rare microfoci of endocervical-type mucinous epithelium. These features indicated multidirectional Mullerian differenti ation in a process that, overall, was consistent with so called florid cyst ic endosalpingiosis. This lesion is to be distinguished from other benign c onditions including multicystic mesothelioma, endometriosis, endocervicosis , florid deep glands of the uterine cervix, and deep Nabothian cysts of the uterine cervix.