Neurotransmitter receptors are found in the neuronal membrane and trigger b
iochemical signals from the outer membrane through the cytoplasm and ultima
tely to the genome. Receptors for numerous steroid hormones, however, act d
irectly at the genome. These 2 pathways apparently interact, and their "cro
ss-talk" may be an important factor in normal neuronal functioning as well
as in psychiatric disorders and the actions of psychotropic drugs.