New modified eremophilanes from the roots of Psacalium radulifolium

Citation
Ml. Garduno-ramirez et al., New modified eremophilanes from the roots of Psacalium radulifolium, J NAT PROD, 64(4), 2001, pp. 432-435
Citations number
27
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
4
Year of publication
2001
Pages
432 - 435
Database
ISI
SICI code
0163-3864(200104)64:4<432:NMEFTR>2.0.ZU;2-P
Abstract
The investigation of the chemical constituents from the roots of Psacalium radulifolium, a member of the matarique complex of medicinal plants, which includes several members of the Asteraceae, resulted in the isolation of fo ur new modified eremophilanes: radulifolin A (4), epi-radulifolin A (5), ra dulifolin B (6), and radulifolin C (7), together with the known natural sub stances cacalol, cacalone, epi-cacalone, O-methyl-1,2-dehydrocacalol, adeno stin A, decompostin, and neoadenostylone. Antimicrobial evaluation of the e xtracts and the isolated compounds indicated that cacalol was the major act ive compound.