New taxane analogues from the needles of Taxus canadensis

Authors
Zhang, JZ Sauriol, F Mamer, O You, XL Alaoui-Jamali, MA Batist, G Zamir, LO
Citation
Jz. Zhang et al., New taxane analogues from the needles of Taxus canadensis, J NAT PROD, 64(4), 2001, pp. 450-455
Citations number
20
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
4
Year of publication
2001
Pages
450 - 455
Database
ISI
SICI code
0163-3864(200104)64:4<450:NTAFTN>2.0.ZU;2-G
Abstract
Eight minor taxanes have been identified for the first time in Taxus canade nsis needles. Four of these metabolites are new taxane analogues: 7-acetyl- 10-deacetyltaxol (1), 2 ' -acetyl-7-epi-cephalomannine (2), 10-deacetyl-10- oxo-7-epi-cephalomannine (3), and 10-acetylglycollylbaccatin VI (4).