Botulinum toxin treatment in cerebral palsy: evidence for a new treatment option

Citation
J. Kirschner et al., Botulinum toxin treatment in cerebral palsy: evidence for a new treatment option, J NEUROL, 248, 2001, pp. S28-S30
Citations number
23
Categorie Soggetti
Neurosciences & Behavoir
Journal title
JOURNAL OF NEUROLOGY
ISSN journal
03405354 → ACNP
Volume
248
Year of publication
2001
Supplement
1
Pages
S28 - S30
Database
ISI
SICI code
0340-5354(200104)248:<S28:BTTICP>2.0.ZU;2-M
Abstract
Intramuscular injections of botulinum toxin type A (BTX-A) have increasingl y been used to reduce spasticity in specific muscle groups in children with cerebral palsy. Targets of therapeutic efforts are improvement of gross mo tor function, alleviation of pain or facilitation of hygienic care. Placebo -controlled studies have shown the local and functional effectiveness of BT X-A for the treatment of dynamic pes equinus. Whether long-term treatment w ith BTX-A improves motor development and delays contractures is still under investigation.