TG and DSC data were used to determine the thermal parameters of prednisone
drug and tablets. Two formulations of prednisone 20 mg were analysed in th
e form of tablets. The TG curves of prednisone drug and tablets A and B dis
played six, eight and seven thermal decomposition processes, respectively.
Analysis of the DSC data pointed to chemical interactions between prednison
e drug and the excipients of tablets A and B, suggested by alterations in t
he melting temperature of prednisone. The analysis revealed that prednisone
drug is more stable than tablets A and B.