Von Recklinghausen's type 1 neurofibromatosis (NF) is a genetic disorder of
neuroectodermal tissue. Arterial involvement has also been recognized. Ste
notic lesions predominate, but aneurysms have been documented as well. Aort
oiliac, visceral, and cervical aneurysms are well represented in the litera
ture, Rarely noted, however, have been peripheral aneurysms. Typically in m
ore proximal vessels, subclavian, femoral, and popliteal aneurysms have bee
n mentioned. We present the case of a patient with type 1 NF and an anterio
r tibial artery aneurysm that was subsequently resected. Neurofibromatous i
nvasion of the vessel was confirmed by means of pathological tests. We thin
k this is the first reported case of a tibial artery aneurysm associated wi
th NF.