Mfr. Brasco et al., Paesslerins A and B: Novel tricyclic sesquiterpenoids from the soft coral Alcyonium paessleri, ORG LETT, 3(10), 2001, pp. 1415-1417
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In the course of our search of new bioactive metabolites from marine invert
ebrates, paesslerins A and B, sesquiterpenoids with an unprecedented tricyc
lic skeleton, were isolated from the subAntarctic soft coral Alcyonium paes
sleri collected at a depth of 200 m near the South Georgia islands, and the
ir structures were elucidated by spectroscopic techniques. These compounds
show moderate cytotoxicity in preliminary assays.