Investigations into the production and interconversion of phomoidrides A-D

Authors
Spencer, P Agnelli, F Sulikowski, GA
Citation
P. Spencer et al., Investigations into the production and interconversion of phomoidrides A-D, ORG LETT, 3(10), 2001, pp. 1443-1445
Citations number
30
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
10
Year of publication
2001
Pages
1443 - 1445
Database
ISI
SICI code
1523-7060(20010517)3:10<1443:IITPAI>2.0.ZU;2-6
Abstract
[GRAPHICS] Fermentation of ATCC 74256 led to the isolation and identification of C7 ep imers of phomoidride A (CP-225,917) and phomoidride B (CP-263,114). We sugg est the names phomoidrides C and D for these new fermentation products, Stu dies on the effect of pH on the distribution of phomoidrides A-D suggest ph omoidride B (CP-263,114) is the first-formed secondary metabolite and the s ource of the remaining three phomoidrides.