A Nozaki-Hiyama-Kishi Ni(II)/Cr(II) coupling approach to the phomactins

Authors
Mi, BY Maleczka, RE
Citation
By. Mi et Re. Maleczka, A Nozaki-Hiyama-Kishi Ni(II)/Cr(II) coupling approach to the phomactins, ORG LETT, 3(10), 2001, pp. 1491-1494
Citations number
31
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
10
Year of publication
2001
Pages
1491 - 1494
Database
ISI
SICI code
1523-7060(20010517)3:10<1491:ANNCAT>2.0.ZU;2-Z
Abstract
Through a unified synthetic strategy, appropriately functionalized bicyclic starting materials can be elaborated via Ni(II)/Cr(II) macrocylization to [9.3.1] bicycles. Elaboration of these core structures allows access to pho mactin C/D analogues and establishes the first synthetic approach to phomac tin A affording an intact octahydrochromene/macrocyclic ring system.