Adenosine- and verapamil-sensitive ventricular tachycardia in the newborn

Two neonates presented with sustained, monomorphic VT. Transesophageal elec trophysiological studies demonstrated that the VTs were initiated with burs t atrial pacing in one and noninducible in the other, and both terminated w ith burst atrial pacing and with adenosine. Oral verapamil suppressed the V Ts in both. Following discontinuation of verapamil at 1 year of age, both c hildren remain free of tachycardia recurrence at 3 and 4 years of age. Thes e cases suggest that cAMP-mediated triggered activity may be responsible fo r some VTs in infancy.