Evaluation of mutagenic activity of several antimalarial extracts from Eupatorium inulaefolium

Eupatorium inulaefolium is used as an antimalarial agent by traditional hea lers of the Tumaco region (Narino-Colombia). Several extracts of this plant have been tested by our laboratory and in vitro antimalarial activity agai nst the FCB-2 strain of Plasmodium falciparum has been confirmed. For this reason, the mutagenic effect of the methanol, dichloromethane, and hexane e xtracts of Eupatorium inulaefolium (number 83377 university of Antioquia he rbarium) were evaluated using the Ames test. None of the extracts evaluated had mutagenic effects on TA-98 or TA-100 strains of Salmonella typhimurium .