A gene coding for SEC14p from Candida glabrata has been cloned and cha
racterized. Nucleotide (nt) sequence analysis reveals an open reading
frame of 909 bp and predicts the synthesis of a polypeptide of 302 ami
no acid (aa) residues. Comparison of nt and aa sequences shows that th
e gene exhibits a much higher homology to the Saccharomyces cerevisiae
(72% and 87%, respectively) than to the Candida albicans (55% and 65%
, respectively) SEC14 gene. (C) 1997 Elsevier Science B.V.