A very simple route to N-methylisatins: Friedel-Crafts acylation of p-substituted N,N-dimethylanilines with oxalyl chloride and DABCO

Authors
Cheng, Y Ye, HL Zhan, YH Cohn, OM
Citation
Y. Cheng et al., A very simple route to N-methylisatins: Friedel-Crafts acylation of p-substituted N,N-dimethylanilines with oxalyl chloride and DABCO, SYNTHESIS-S, (6), 2001, pp. 904-908
Citations number
27
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
6
Year of publication
2001
Pages
904 - 908
Database
ISI
SICI code
0039-7881(200105):6<904:AVSRTN>2.0.ZU;2-2
Abstract
N-Methylisatins were obtained in high yields in a one-pot reaction by the F riedel-Crafts acylation of p-substituted N,N-dimethylanilines by oxalyl chl oride in the presence of a base. The best results were obtained using DABCO .