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Synthesis of enantiomeric 4-hydroxypropranolols from 1,4-dihydroxynaphthalene
Authors
Kumamoto, T
Aoyama, N
Nakano, S
Ishikawa, T
Narimatsu, S
Citation
T. Kumamoto et al., Synthesis of enantiomeric 4-hydroxypropranolols from 1,4-dihydroxynaphthalene, TETRAHEDR-A, 12(5), 2001, pp. 791-795
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 →
ACNP
Volume
12
Issue
5
Year of publication
2001
Pages
791 - 795
Database
ISI
SICI code
0957-4166(20010402)12:5<791:SOE4F1>2.0.ZU;2-M
Abstract
Both (R)- and (S)-enantiomes of 4-hydroxypropranolol were effectively prepa red from 1,4-dihydroxynaphthalene in eight steps. The overall yields were a round 30%. (C) 2001 Elsevier Science Ltd. All rights, reserved.