Use of mass spectrometry-derived data to annotate nucleotide and protein sequence databases

Authors
Mann, M Pandey, A
Citation
M. Mann et A. Pandey, Use of mass spectrometry-derived data to annotate nucleotide and protein sequence databases, TRENDS BIOC, 26(1), 2001, pp. 54-61
Citations number
42
Categorie Soggetti
Biochemistry & Biophysics
Journal title
TRENDS IN BIOCHEMICAL SCIENCES
ISSN journal
09680004 → ACNP
Volume
26
Issue
1
Year of publication
2001
Pages
54 - 61
Database
ISI
SICI code
0968-0004(200101)26:1<54:UOMSDT>2.0.ZU;2-S
Abstract
Mass spectrometry-based proteomic methodologies can be used to annotate bot h nucleotide and protein sequence databases. Because such data have to be d erived from proteins, they can be used to identify coding regions of the ge nome as weft as provide the complete primary sequence of proteins and their expression patterns and post-translational modifications.