Telomerase inhibitors

There has been a vast increase in telomerase research over the past several years, with many different pre-clinical approaches being tested for inhibi ting the activity of this enzyme as a novel therapeutic modality to treat m alignancy. In this review, we will provide some basic background informatio n about telomeres and telomerase and then discuss the pros, cons and challe nges of the approaches that are currently under investigation, and what we might expect in the future of this emerging field.