Protein phosphatase 5 in signal transduction

Authors
Chinkers, M
Citation
M. Chinkers, Protein phosphatase 5 in signal transduction, TRENDS ENDO, 12(1), 2001, pp. 28-32
Citations number
45
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
TRENDS IN ENDOCRINOLOGY AND METABOLISM
ISSN journal
10432760 → ACNP
Volume
12
Issue
1
Year of publication
2001
Pages
28 - 32
Database
ISI
SICI code
1043-2760(200101/02)12:1<28:PP5IST>2.0.ZU;2-7
Abstract
Protein phosphatase 5 (PP5) possesses unique biochemical properties, which include its tetratricopeptide repeat (TPR) targeting/regulatory domain and its ability to he activated by lipids. PP5 has been studied as a paradigm f or TPR protein structure and function. Roles for PP5 in signal transduction are emerging:from cell cycle regulation and signaling by nuclear receptors , to possible regulation of membrane receptors and ion channels.