To investigate the animals infected with Borna disease virus (BDV) in Xinji
ang, China, we examined for BDV antibodies in the sera from groups of 20 ho
rses, sheep and cattle, and from 165 wild rodents (18 species) by ELISA and
immunoblot. The serological study disclosed the presence of antibodies to
both BDV-p24 and -p40 in the horses (20%) and sheep (25%), whereas no appar
ent positive reaction was detected either in cattle or rodents. The results
suggested that BDV is prevalent in horses and sheep in the district invest
igated. (C) 2001 Elsevier Science B.V. All rights reserved.