With recent technologic advances there has been a resurgence of interest in
implantable insulin infusion devices, h satisfactory closed loop system ha
s been elusive. Open loop systems include the pump, delivery catheter, and
patient pump communicator, Several such systems are currently undergoing cl
inical investigation. Implantable pumps can be placed with minimal morbidit
y. Insulin underdelivery is the most frequent long-term problem. Several re
cent studies suggest that implantable pumps can safely and effectively main
tain good glucose control, The development of a satisfactory implantable cl
osed loop system will be the nest step in this technology.