Alcohol biomarkers: Clinical significance and biochemical basis

This article represents the proceedings of a symposium at the 2000 ISBRA Me eting in Yokohama, Japan. The chairs were Raj Lakshman and Mikihiro Tsutsum i. The presentations were (1) Sialic acid index of apolipoprotein J: A new marker for chronic alcohol consumption, by P. Ghosh and M. R. Lakshman; (2) Microheterogeneity of serum glycoproteins in alcoholics, by M. Tsutsumi an d S. Takase; (3) Probing protein-ethanol adducts with combinatorial peptide libraries displayed by filamentous phage, by H. Anni, O. Nikolaeva, and Y. Israel Y; (4) Carbohydrate-deficient transferrin as a marker for heavy alc ohol use: What have we learned; Where do we go from here, by R. F. Anton; ( 5) Sensitivity and specificity of carbohydrate -deficient transferrin in dr inking experiments and different patient groups, by O. M. Lesch; (6), Trans ferrin variants interfere with the measurement of carbohydrate-deficient tr ansferrin, by A. Helender, G. Eriksson, and J-O. Jeppson; and (7) Chronic e thanol on protein trafficking in liver, by P. Marmillot, M. N. Rao, and M. R. Lakshman.