This article represents the proceedings of a symposium at the 2000 ISBRA Me
eting in Yokohama, Japan. The chairs were Helmut K. Seitz and Shohei Matsuz
aki. The presentations were (1) Alcohol dehydrogenase-2 and aldehyde dehydr
ogenase-2 genotype and cancer risk for upper aerodigestive tract in Japanes
e alcoholics, by Akira Yokoyama; (2) The role of acetaldehyde in alcohol-as
sociated carcinogenesis, by Nils Homann; (3) High salivary acetaldehyde lev
els after a moderate dose of alcohol in ALDH2-deficient subjects, by Satu V
akevainen; (4) Alcohol and vitamin A interactions, by Xian Dong Wang; and (
5) Alcohol and colorectal cancer, by Helmut K. Seitz.