This article represents the proceedings of a symposium at the ISBRA Meeting
in Yokohama, Japan. The chairs were A. D. LC and K. Kiianmaa. The presenta
tions were (1) Alcohol reward and aversion, by C. L. Cunningham; (2) The ro
le of sensitization of neuronal mechanisms in ethanol self-administration,
by J. A. Engel, M. Ericson, and B. Soderpalm; (3) Alcohol self-administrati
on in dependent animals: Neurobiological mechanisms, by G. F. Koob, A. J. R
oberts, and F. Weiss; (4) Stress and relapse to alcohol, by A. D. Le; (5) A
lcohol-preferring AA and alcohol-avoiding ANA rats differ in locomotor acti
vation induced by repeated morphine injections, by P. Hyytia, S. Janhunen,
J. Mikkola, P. Backstrom, and K. Kiianmaa; and (6) Initial sensitivity and
acute functional tolerance to the hypnotic effects of ethanol in mice genet
ically selected for mild and severe ethanol withdrawal convulsions, by I. P
onomarev and J. C. Crabbe.