Tracheal gas insufflation is a technique in which gas is injected intratrac
heally during positive pressure ventilation. The fresh gas rinses expired g
as fi-om the tracheal tube and anatomical dead space, aiding carbon dioxide
elimination. This reduces ventilatory volume and pressure, helping to redu
ce ventilator-induced lung damage. Complications of tracheal gas insufflati
on include interference with ventilator function, tracheal damage and barot
rauma. Expiratory washout is a variation of tracheal gas insufflation. We d
esigned and constructed an original expiratory washout system and evaluated
its safety and performance in lung and animal models. We found that expira
tory limb and tracheal tube occlusion tests caused the device to disable it
self at acceptable intratracheal pressures. We also demonstrated up to 31%
reduction in tidal volume compared with conventional ventilation, supportin
g the possibility of using this device clinically to lessen volutrauma. We
concluded that aspects of this design might alleviate many of the safety co
ncerns of using tracheal gas insufflation.