In vitro activities of moxifloxacin and ether fluoroquinolones against Mycoplasma pneumoniae

Authors
Hamamoto, K Shimizu, T Fujimoto, N Zhang, Y Arai, S
Citation
K. Hamamoto et al., In vitro activities of moxifloxacin and ether fluoroquinolones against Mycoplasma pneumoniae, ANTIM AG CH, 45(6), 2001, pp. 1908-1910
Citations number
11
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
6
Year of publication
2001
Pages
1908 - 1910
Database
ISI
SICI code
0066-4804(200106)45:6<1908:IVAOMA>2.0.ZU;2-H
Abstract
A total of 105 isolates of Mycoplasma pneumoniae were evaluated for suscept ibility to moxifloxacin, sparfloxacin, levofloxacin, and ciprofloxacin. Mox ifloxacin, a newly synthesized compound, showed the greatest activity. The MICs and MBCs at which 50 and 90% of isolates were affected were 0.15 (MIC5 0 and MBC50) and 0.3 mug/ml (MIC90 and MBC90) respectively. The results ind icate that moxifloxacin might be promising an antimycoplasmal agent.