Sarcoidosis presenting as an intramedullary spinal cord lesion

Objectives: Sarcoidosis affects the spinal cord in only 0.43% of patients w ith sarcoidosis. Usually there is systemic involvement prior to the develop ment of cord lesions. We present a case of sarcoid isolated to the intramed ullary spinal cord, which was a diagnostic and therapeutic challenge. We re view the case and then present a review of the literature with an emphasis on presentation, diagnosis and treatment. Methods: We have reviewed a patie nt who presented with an isolated sarcoid granuloma affecting the cervical spinal cord. All pertinent history and physical information was extracted f rom the patient's chart and through patient interview. Laboratory, radiogra phic and pathological investigations are presented. Results and conclusions : Fourteen patients have been reported with isolated intramedullary spinal cord sarcoidosis. Current practice supports the role of surgery for biopsy; mainstay of treatment is corticosteroids.