Competitive uptake of porphyrin and LDL via the LDL receptor in glioma cell lines: flow cytometric analysis

Authors
Shibata, Y Matsumura, A Yoshida, F Yamamoto, T Nakai, K Nose, T Sakata, I Nakajima, S
Citation
Y. Shibata et al., Competitive uptake of porphyrin and LDL via the LDL receptor in glioma cell lines: flow cytometric analysis, CANCER LETT, 166(1), 2001, pp. 79-87
Citations number
14
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
CANCER LETTERS
ISSN journal
03043835 → ACNP
Volume
166
Issue
1
Year of publication
2001
Pages
79 - 87
Database
ISI
SICI code
0304-3835(20010510)166:1<79:CUOPAL>2.0.ZU;2-O
Abstract
We examined the simultaneous uptake of porphyrin and (LDL) by four establis hed cell lines of glioma and normal fibroblasts using flow cytometry (FCM). The results indicated porphyrin and LDL showed competitive conjugation wit h the LDL receptor. These results support the theory of the porphyrin uptak e via the LDL receptor. (C) 2001 Elsevier Science Ireland Ltd. All rights r eserved.