Neuroimaging and substance abuse disorders in the year 2000

This review summarizes the findings of substance abuse research published t hroughout the year 2000, which used noninvasive neuroimaging approaches. Th ese findings encompass abnormalities in brain morphometry, integrated brain activity, cognitive activation and neurochemical systems associated with v arious aspects of substance abuse disorders. The methodological strengths a nd weaknesses of these studies are critically addressed, and future researc h directions are outlined. Curr Opin Psychiatry 14:179-185. (C) 2001 Lippin cott Williams & Wilkins.