Kinetic analysis of oxidation of dopamine by sodium N-chlorobenzenesulphonamide in perchloric acid medium: A mechanistic approach

Authors
Puttaswamy,"Anuradha, TM Mahadevappa, KL
Citation
Tm. Puttaswamy,"anuradha et Kl. Mahadevappa, Kinetic analysis of oxidation of dopamine by sodium N-chlorobenzenesulphonamide in perchloric acid medium: A mechanistic approach, I J CHEM A, 40(5), 2001, pp. 514-518
Citations number
19
Categorie Soggetti
Chemistry
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY
ISSN journal
03764710 → ACNP
Volume
40
Issue
5
Year of publication
2001
Pages
514 - 518
Database
ISI
SICI code
0376-4710(200105)40:5<514:KAOOOD>2.0.ZU;2-A
Abstract
Kinetics of oxidation of dopamine (DPM) by sodium N-chlorobenzenesulphonami de (chloramine-B or CAB) in perchloric acid medium has been studied at 40 d egreesC. The rate shows first order dependence in [CAB](o) fractional order in [DPM](o), and inverse fractional order in [H+]. The effects of dielectr ic constant and solvent isotope have been studied. Michaelis-Menten type of kinetics have been proposed and activation parameters for the rate determi ning step have been computed. A mechanism consistent with the observed kine tics is proposed and discussed.