A 21-year-old man presented persistent dry cough, general malaise, loss of
appetite, decreased sexual desire and double vision. Chest radiograph revea
led a mass shadow in the left upper lobe, Histopathological diagnosis of th
e tumor was squamous cell carcinoma, Brain computed tomography and magnetic
resonance imaging revealed a metastasis to the pituitary gland. Hypopituit
arism was diagnosed by pituitary function tests. Diabetes insipidus was abs
ent and the function of the posterior lobe of the pituitary gland was prese
rved. Hypopituitarism due to pituitary metastasis is a rare complication of
lung cancer, and has never been reported in a patient as young as 21 years
old.