Glomerulonephritis after methicillin-resistant Staphylococcus aureus infection resulting in end-stage renal failure

A 58-year-old man developed proteinuria and renal dysfunction following pne umonia caused by methicillin-resistant Staphylococcus aureus (MRSA). Vancom ycin was administered, and prednisolone pulse therapy and plasmapheresis we re performed. Subsequently, serum creatinine was decreased. Eight months la ter, creatinine and CRP were again elevated, and MRSA was detected, Vancomy cin was again administered and plasmapheresis was performed. However, renal function was not improved and continuous hemodialysis was initiated. This case indicates that complete eradication of MRSA is necessary to treat MRSA -associated glomerulonephritis, and if this is not attained, a permanent lo ss of renal function occurs.