Spontaneous rupture of the amyloid spleen in a case of usual interstitial pneumonia

We describe a rare case of secondary amyloidosis associated with usual inte rstitial pneumonia (UIP), who died from spontaneous rupture of the amyloid spleen. A 68-year-old man was admitted to evaluate to his interstital lung disease, Chest radiography showed reticular shadow in bilateral lower lung fields. Two years later, he suddenly felt severe abdominal pain. In spite o f maximum therapy, he died from hypovolemic shock, Postmortem examination r evealed massive intraabdominal hemorrhage, The diagnosis of lung disease wa s UIP and amyloid A type deposits were observed in various organs including the ruptured spleen.