The relationship between religion and mental health has been debated for ce
nturies. History shows that religious organizations were often the first to
offer compassionate care to the mentally ill; however, for hundreds of yea
rs the religious establishment also persecuted the mentally ill. Neverthele
ss, the first form of psychiatric care in Western Europe and the US was kno
wn as 'moral treatment', in which religion played a significant role. The t
eachings of Freud and others during the early twentieth century concerning
the neurotic influences of religion have had an enormous impact on the fiel
d, nullifying the quite favorable views toward religion held by nineteenth
century psychiatrists. In this article, we review research that has found b
oth negative and positive associations between religious involvement and me
ntal health. We then examine the implications of this research for the clin
ical practice of psychiatry in the twenty-first century.