The case of a 63-year-old woman with a solitary pulmonary nodule (SPN) is r
eported. Surgical wedge resection revealed an hamartoma. Digital examinatio
n of the lung parenchyma showed an unexpected (not previously visualized by
thoracic imaging) second nodule that intraoperative frozen examination rev
ealed an adenocarcinoma. The operation was completed with a right upper lob
ectomy and complete lymphoadenectomy. The authors recommend an early open s
urgical procedure for any SPNs with risk factors for developing lung cancer
.