M. Quirynen et al., The intra-oral translocation of periodontopathogens jeopardises the outcome of periodontal therapy - A review of the literature, J CLIN PER, 28(6), 2001, pp. 499-507
Background: Although periodontitis has a multi-factorial aetiology, the suc
cess of its therapy mainly focuses on the eradication/reduction of the exog
enous/endogenous periodontopathogens. Most of the species colonise several
niches within the oral cavity (e.g. the mucosae, the tongue, the saliva, th
e periodontal pockets and all intra-oral hard surfaces) and even in the ore
-pharyngeal area (e.g., the sinus and the tonsils).
Methods: This review article discusses the intra-oral transmission of perio
dontopathogens between these niches and analyses clinical studies that supp
ort the idea and importance of such an intra-oral translocation.
Results and conclusions: Based on the literature, the ore-pharyngal area sh
ould indeed be considered as a microbiological entity. Because untreated po
ckets jeopardise the healing of recently instrumented sites, the treatment
of periodontitis should involve "a one stage approach" of all pathologic po
ckets (I-stage full-mouth disinfection) or should at least consider the use
of antiseptics during the intervals between consecutive instrumentations,
in order to prevent a microbial translocation of periodontopathogens during
the healing period. For the same reason, regeneration procedures or the lo
cal application of antibiotics should be postponed until a maximal improvem
ent has been obtained in the remaining dentition. This more global approach
offers significant additional clinical and microbiological benefits.