Lipomas of the gastrointestinal tract are uncommon tumors. Almost all gastr
ointestinal lipomas are submucosal or subserosal, and most are asymptomatic
, although they may cause abdominal pain, bowel obstruction, and gastrointe
stinal bleeding. The diagnosis of gastrointestinal lipoma is usually not ma
de before surgery. We present a case of colonic intussusception caused by a
lipoma that was located in the muscular layer of the colon and was diagnos
ed preoperatively by sonography. The descending colon appeared edematous an
d thick. There was layering within the lumen of the descending colon, mimic
king the target sign. At the distal end of the intussusception, there was a
4.7-cm, hyperechoic, rounded lesion with a smooth margin. Surgery revealed
a polypoid mass originating from the splenic flexure and causing intussusc
eption of the colon, and pathologic analysis confirmed the diagnosis of lip
oma of the muscular layer of the colon. (C) 2001 John Wiley &, Sons, Inc.