Analysis of the aqueous humor filtration according to the type of implantsafter deep sclerectomy in the rabbit

Purpose: The purpose of this study was to compare the aqueous humor outflow using three type of implants after deep sclerectomy. A numeric imaging sys tem with ICG and fluorescein angiography was used. The evolution over time was recorded, while filtration and outflow facility were measured. Material and Methods: Numeric imaging system with ICG and fluorescein angio graphy were performed before and after deep sclerectomy at regular interval s after surgery. Both resorbable (collagen) and non-resorbable (hema) intra scleral devices have been tested in eight rabbits. The resorbtion time of t he collagen implants has been monitored using UBM technique. The outflow fa cility was measured with the technique of anterior chamber canulation and c onstant pressure method. Results: The resorbable collagen implants could be observed with UBM and an giography during the first six weeks postoperatively. The image of the non- resorbable Hema implant remained clearly visible over time. New drainage ve ssels were observed around the filtering bleb. The filtration significantly increased as the outflow facility improved after surgery, while the intrao cular pressure remained stable over time. Conclusion: This conjunction of UBM, angiography and outflow measurement al lowed us to study and compare three types of implants used as space maintai ner after deep sclerectomy, and analyse their effect on the aqueous filtrat ion and outflow facility.