E. Anagnostou et al., Contraversive eye deviation during deep brain stimulation of the globus pallidus internus, NEUROLOGY, 56(10), 2001, pp. 1396-1399
Clinical signs help determine correct electrode positioning during stereota
ctic implantation for chronic high-frequency pallidal stimulation in Parkin
son's diease (PD). The authors describe a patient who had marked, sustained
, contraversive eye deviation caused by stimulation during pallidal surgery
. The underlying mechanism is probably an excitation of fibers in the inter
nal capsule by volume-conducted current spread. Such conjugate eye deviatio
n is thus not necessarily an indication of incorrect electrode placement.