CYTOMEGALOVIRUS PRIMOINFECTION AND PREGNA NT-WOMEN - EPIDEMIOLOGIC-STUDY ON 1100 WOMEN AT LIMOGES

During 13 months, 1101 women attending for antenatal care at Limoges U niversity Hospital vc ere prospectively studied to determine the preva lence of Cytomegalovirus (CMV) antibodies 47,9 % of these women were C MV seropositive. Ethnic group was strongly associated with CMV status : 42,6% of metropolitan and 94,5 % of immigrant women were seropositiv e. Seropositivity was associated with increasing parity and older age. The risk of a susceptible woman to acquire CMV infection during pregn ancy is 0,7 %. Among the 4 seroconversions, 3 children were infected, with developmentally and neurologically normal status in one case, mod erate earing damage in an other case and a disseminated infection in t he third case requiring a provoked abortion.