Desmosis coli is a disturbance of the intramural connective tissue mesh net
work of the colonic wall which can lead to a hypoperistalsis syndrome with
chronic constipation in the absence of any anomaly of the vegetative gut in
nervation. The condition typically occurs in infants and adolescents; howev
er, as an incomplete form, desmosis coli can also cause chronic constipatio
n in adults, as demonstrated in this case report.