Reversal of lidocaine with epinephrine epidural anesthesia using epidural saline washout

Citation
Bt. Sitzman et al., Reversal of lidocaine with epinephrine epidural anesthesia using epidural saline washout, REG ANES PA, 26(3), 2001, pp. 246-251
Citations number
24
Categorie Soggetti
Aneshtesia & Intensive Care
Journal title
REGIONAL ANESTHESIA AND PAIN MEDICINE
ISSN journal
10987339 → ACNP
Volume
26
Issue
3
Year of publication
2001
Pages
246 - 251
Database
ISI
SICI code
1098-7339(200105/06)26:3<246:ROLWEE>2.0.ZU;2-H
Abstract
Background and Objectives: Prolonged motor and sensory block following epid ural anesthesia can be associated with extended postoperative care unit sta ys and patient dissatisfaction. Previous studies have demonstrated a more r apid motor recovery following the administration of epidural crystalloids i n patients who had received plain bupivacaine and lidocaine epidural anesth esia. However, epinephrine is commonly added to local anesthetics to improv e the quality and prolong the duration of the epidural block. The objective of this study was to determine the relationship of 0.9% NaCl epidural cath eter flush volume (i.e., washout) to the recovery of motor and sensory bloc k in patients undergoing 2% lidocaine with epinephrine epidural anesthesia. Methods: A prospective. randomized, double-blind study design was utilized. Thirty-three subjects scheduled for elective gynecologic or obstetrical su rgical procedures underwent epidural anesthesia using 2% lidocaine with epi nephrine (1:200,000). A T4 dermatome level of analgesia, determined by toot hpick prick, was maintained intraoperatively. Following surgery, subjects w ere randomized to 1 of 3 treatment groups. Group 1 (control, n = 11) receiv ed no epidural 0.9% NaCl (normal saline [NS]) postoperatively. Group 2 (15 mL NS X 1, n = 10) received an epidural bolus of 15 mL NS. Group 3 115 mL N S x 2, n = 12) received an epidural bolus of 15 mt NS postoperatively and a second 15-mL NS bolus 15 minutes later. Assessment of motor and sensory bl ock was performed at 15-minute intervals until complete motor and sensory r ecovery. Results: Times to partial and full motor and sensory recovery were signific antly faster in the epidural NS groups than in the control group. Full moto r recovery was more rapid in subjects receiving two 15-mL NS epidural NS bo luses (30 mL total) compared with those receiving a single 15-mL. NS bolus (108 +/- 9 min v 136 +/- 13 min) and significantly faster than control grou p subjects (153 +/- 14 min). Both NS X 1 and NS x 2 epidural bolus groups e xperienced significantly reduced times to complete sensory recovery when co mpared with the control group INS X 1 = 154 +/- 13 min, NS x 2 = 153 +/- 9 min, control 195 +/- 14 min). Conclusions: A more rapid recovery of motor and sensory block in patients u ndergoing 2% lidocaine with epinephrine epidural anesthesia can be achieved with the use of 30 mt NS epidural washout.