Nucleophilic substitution of hydrogen in activated nitroarenes by phenylacetonitrile carbanion

Authors
Orlov, VY Sokovikov, YV Kotov, AD Starikov, AA
Citation
Vy. Orlov et al., Nucleophilic substitution of hydrogen in activated nitroarenes by phenylacetonitrile carbanion, RUSS J ORG, 36(12), 2000, pp. 1735-1738
Citations number
8
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
10704280 → ACNP
Volume
36
Issue
12
Year of publication
2000
Pages
1735 - 1738
Database
ISI
SICI code
1070-4280(200012)36:12<1735:NSOHIA>2.0.ZU;2-S
Abstract
General relations holding in nucleophilic substitution of hydrogen in para- substituted nitroarenes by phenylacetonitrile carbanion were analyzed in te rms of the Klopman reactivity indices. Requirements to the substrate struct ure were determined, which restrict the scope of application of this method to synthesis of 2,1-benzisoxazole derivatives.