Tetrazoles: XLI. Alkylation of 1-aryltetrazol-5-ones

The site of alkylation of 1-aryltetrazol-5-ones under conditions of phase-t ransfer catalysis in the systems liquid-liquid and solid-liquid does not de pend on the nature of alkylating agent and structure of phase-transfer cata lyst. Alkylation of 1-phenyltetrazol-5-one with dibromoalkanes provides a c onvenient route to bis-tetrazoles and 4-bromoalkyl derivatives. The latter can be used for synthesis of functionally substituted tetrazoles.