Synthesis of 13-Aza-14-oxa- and 13,14-diazaprostanoids

Authors
Khlebnikova, TS Lakhvich, FA
Citation
Ts. Khlebnikova et Fa. Lakhvich, Synthesis of 13-Aza-14-oxa- and 13,14-diazaprostanoids, RUSS J ORG, 36(11), 2000, pp. 1595-1600
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
10704280 → ACNP
Volume
36
Issue
11
Year of publication
2000
Pages
1595 - 1600
Database
ISI
SICI code
1070-4280(200011)36:11<1595:SO1A1>2.0.ZU;2-7
Abstract
A procedure was developed for preparation of previously unknown 13-aza-14-o xa- and 13,13-diazaprostanoids proceeding from 2-(omega -methoxycarbonylalk anoyl)cyclopentane-1,3-diones that comprised the transformation of the ment ioned beta -triketones effected by diazomethane into 3-methoxy-2-(omega -me thoxycarbonylalkanoyl)-2-cyclopenten-1-ones and further vinylog substitutio n of the enol ethers obtained with amyloxyamine or phenylhydrazine.