Nf. Bondar et al., Synthesis and dehydration of exo-2-(3-R-5-isoxazolyl)-5,6,6-trimethylbicyclo[2.2.1]heptan-endo-2-ols, RUSS J ORG, 36(11), 2000, pp. 1607-1611
The reaction of nitrile oxides with 2-exo-ethynyl-5,6,6-trimethyihicyclo[2.
2.1]heptan-2-endo-ol resulted in 2-exo-(3-R-5-isoxazolyl)-5,6,6-trimethylbi
cyclo[2.2.1]heptan-2-endo-ols that on treatment with methanesulfonyl chlori
de in pyridine underwent dehydration to afford a mixture of 2-exo-(3-R-5-is
oxazolyl)-5,5,6-trimethyl bicyclo[2.2.1]hept-2-ene and 2-(3-R-5-Isoxazolyl)
-4,7,7-trimethylbicyclo[2.2.1]hept-2-ene in 3:1 ratio.