Streptococcus agalactiae endocarditis and giant pyomyoma simulating ovarian cancer

Group B streptococcus (Streptococcus agalactiae) is a common etiology of ba cteremia among adults. Pyomyoma is a rare infectious complication of uterin e leiomyomas, We report the case of a diabetic postmenopausal woman with a giant pyomyoma simulating an ovarian cancer. It was associated with S agala ctiae endocarditis and deep venous thrombosis of the right external iliac a nd femoral veins. Treated initially with intravenous penicillin, amikacin, and anticoagulation, the patient later had abdominal hysterectomy with an u neventful recovery. We also review the cases of pyomyoma reported since 194 5. Of 14 cases described (including ours), mortality was 21%, Endocarditis was never reported in association with pyomyoma, The presence of bacteremia and a leiomyoma should raise suspicion for this disease.