Thrombocytopenia caused by splenic hamartoma: resolution after splenectomy

We report a rare case of isolated thrombocytopenia due to a large hamartoma of the pulposal type, which resolved with splenectomy in a 46-year-old man . Although hamartomas are usually found incidentally, they may cause hemato logic disturbances such as thrombocytopenia, anemia, or splenic rupture. Th e diagnosis of splenic hamartoma is difficult to make preoperatively. Splen ectomy is important in excluding malignant tumors from the diagnosis when t he etiology of a splenic mass is unclear and ameliorating hematologic sympt oms related to hamartomas.