IR AND ESR STUDY OF CU(II)-NITRAZEPAM COMPLEXES

The CuL2X2 (L = o-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one, kno wn as nitrazepam, X = Cl, Br) complexes were prepared and investigated by IR, ESR and magnetic susceptibility measurements. The IR spectra s uggest that the Cu(II) ion is coordinated by two nitrogen and two halo gen atoms; The powder ESR spectrum at room temperature of CUL2Br2 is q uasiisotropic, while that of CuL2Cl2 is characteristic of an axial mon omeric species with small rhombic distortions. The isotropic ESR spect ra of these compounds in DMF and Py solutions suggest the presence of pseudo-tetrahedral monomeric species. Two different monomeric species were evidenced in Cu(II)-nitrazepam solutions adsorbed onto NaY zeolit e. (C) 1997 Elsevier Science B.V.