Intramitochondrial recombination - is it why some mitochondrial genes sleep around?

Citation
M. Dowton et Njh. Campbell, Intramitochondrial recombination - is it why some mitochondrial genes sleep around?, TREND ECOL, 16(6), 2001, pp. 269-271
Citations number
24
Categorie Soggetti
Environment/Ecology
Journal title
TRENDS IN ECOLOGY & EVOLUTION
ISSN journal
01695347 → ACNP
Volume
16
Issue
6
Year of publication
2001
Pages
269 - 271
Database
ISI
SICI code
0169-5347(200106)16:6<269:IR-IIW>2.0.ZU;2-T
Abstract
A new paper by Kajander et al. undermines the general view that mitochondri a do not recombine. The authors discovered the existence of 'sublimons', re arranged mitochondrial genomes present at very low levels in healthy human patients. Crucially, the different rearranged mitochondrial genomes can the oretically be interconverted through intramitochondrial recombination. The putative operation of intramitochondrial recombination should impact on our ideas of how mitochondrial genes evolve, particularly with respect to how mitochondrial genomes rearrange.