Identification and analysis of eukaryotic promoters: recent computational approaches

Citation
U. Ohler et H. Niemann, Identification and analysis of eukaryotic promoters: recent computational approaches, TRENDS GEN, 17(2), 2001, pp. 56-60
Citations number
30
Categorie Soggetti
Molecular Biology & Genetics
Journal title
TRENDS IN GENETICS
ISSN journal
01689525 → ACNP
Volume
17
Issue
2
Year of publication
2001
Pages
56 - 60
Database
ISI
SICI code
0168-9525(200102)17:2<56:IAAOEP>2.0.ZU;2-E
Abstract
The DNA sequence of several higher eukaryotes is now complete, and we know the expression patterns of thousands of genes under a variety of conditions . This gives us the opportunity to identify and analyze the parts of a geno me believed to be responsible for most transcription control-the promoters. This article gives a short overview of the state-of-the-art techniques for computational promoter localization and analysis, and comments on the most recent advances in the field.